Progestin, To Help Patients Progesterone Deficiency, Progestin is a synthetic progestogen that has an effect similar to natural progesterone. Progestin is a hormone and is used by both men and women for different purposes.
Progestins are prescribed for several reasons:
1. To properly regulate the menstrual cycle and stop treating unusual menstrual periods (amenorrhea). Progestins work by causing changes in the uterus.
After a number of progestin in the blood decreases, the uterine lining begins to be apart of and vaginal bleeding occurs (menstrual period). Progestins help other hormones start and stop the menstrual cycle.
2. To help pregnancy occur during egg donor or infertility procedures in women does not produce enough progesterone. Progesterone is also given to help maintain the pregnancy if the body is less capable.
3. To prevent the thickening of the uterine lining (endometrial hyperplasia) in postmenopausal women who were treated with estrogen for ovarian hormone therapy or ovarian hormone therapy (OHT).
4. To treat the pain associated with endometriosis, a condition where endometrial tissue that lines the uterus migrate to other female organs.
5. To treat a condition called endometriosis, to help prevent endometrial hyperplasia, or to treat abnormal bleeding, and weight of the uterus (dysfunctional uterine bleeding) by starting or stopping the menstrual cycle.
6. To help treat kidney cancer, uterine, and breast. Progestins help change the cancer cell's ability to react to hormones and other proteins that cause tumor growth.In this way, progestins can stop tumor growth.
7. To test the body to produce certain hormones, like estrogen.
8. To treat loss of appetite, severe weight loss, and muscle weakness in patients with AIDS or cancer by producing specific proteins that cause increased appetite and weight.
Progestins can also be used for other conditions as determined by your doctor.Progestins can help other hormones work properly, helps prevent anemia (low iron levels in the blood), too much blood loss due to menstruation, and uterine cancer.Progestins are available only by prescription.
Progestins are also used in certain patients with medical conditions as follows:
Carcinoma of prostate
Corpus luteum insufficiency
Hot flashes, night sweats
Polycystic ovary syndrome
Mature or premature puberty
Packaging
This product is available in tablet dosage forms, suspensions, capsules, jelly, cream, and kits.
Dose
Medroxyprogesterone tablet dosage forms:
1. For controlling abnormal bleeding and dysfunctional uterine bleeding or treating unusual menstrual periods (amenorrhea):
Adults and teenagers: 5 to 10 mg per day for five to ten days as directed by your doctor.
2. To prepare the uterus menstrual period:
Adults and teenagers: 10 mg per day for five or ten days as directed by your doctor.
To prevent the thickening of the uterine lining (endometrial hyperplasia) when taking estrogen in ovarian hormone therapy in postmenopausal women:
1. Adults: When taking estrogen each day on day one to day 25; 5 to 10 mg per day for ten to fourteen or more each month as directed by your doctor. Or your doctor may want the patient to drink 2.5 or 5 mg per day without stopping. Your doctor will help determine the number of tablets is best for the patient and when to drink it.
Dosage form of an injection into the muscle:
To treat kidney or uterine cancer:
Adults and teenagers: At first, 400-1000 mg injected into a muscle as a single dose once a week. Then, your doctor may lower the dose to 400 mg or more once a month.
For injection dosage form under the skin:
To treat the pain of endometriosis:
Adults and teenagers: 104 mg injected under the skin of the thigh or abdomen every three months (12 to 14 weeks) no more than 2 years.
To megestrol suspension dosage forms:
To treat loss of appetite (anorexia), muscle weakness (cachexia), or weight loss due to AIDS:
Adults and teenagers: 800 mg per day during the first month. Your doctor may want the patient to take 400 or 800 mg daily for three months.
To megestrol tablet dosage forms:
For treating breast cancer:
Adults and teenagers: 160 mg per day as a single dose or in divided doses for two months or more.
To treat uterine cancer:
Adults and teenagers: 40-320 mg daily for two months or more.
To treat loss of appetite (anorexia), muscle weakness (cachexia), or weight caused by cancer:
Adults and teenagers: 400 to 800 mg per day.
Norethindrone tablet dosage forms:
For controlling abnormal bleeding and dysfunctional uterine bleeding or stopping of menstrual periods that is not usual (amenorrhea):
Adults and teenagers: 2.5 to 10 mg per day from day 5 to day 25 (calculated from the first day of last menstrual cycle). Your doctor may want the patient to take medicine only for five to ten days.
To treat endometriosis:
Adults and teenagers: At first, 5 mg daily for two weeks. Your doctor may increase your dose slowly to 15 mg daily for six to nine months. Let your doctor know if the patient's menstrual period has begun. physician may want the patient to drink more or may want the patient to stop taking medication for a short time.
Progesterone capsule dosage form:
To prevent the thickening of the uterine lining (endometrial hyperplasia) when taking estrogen for ovarian hormone therapy in postmenopausal women:
Adults: 200 mg per day at bedtime for 12 continuous days per 28 day cycle of estrogen treatment each month.
To treat menstrual periods stop the unusual (amenorrhea):
Adults: 400 mg per day at bedtime for ten days.
Vaginal gel dosage forms:
To stop an unusual menstrual periods (amenorrhea):
Adults and teenagers: 45 mg once daily for up to six doses. The dose may be increased to 90 mg once daily for six doses if needed.
For use with infertility procedures:
Adults and teenagers: 90 mg once or twice a day. If pregnancy occurs, treatment can be continued until 10-12 weeks.
Injectable dosage forms:
For controlling abnormal bleeding and dysfunctional uterine bleeding or stopping of menstrual periods that is not usual (amenorrhea):
Adults and teenagers: 5 to 10 mg per day injected into a muscle for six to ten days.Your doctor may want patients to receive 100 or 150 mg injected into a muscle as a single dose. Sometimes your doctor may want apsien taking estrogen. If the menstrual period had started, the doctor will advise patients to stop taking medication.
Vaginal suppository dosage forms:
To maintain the pregnancy (at ovulation and in early pregnancy):
Adults and teenagers: 25 mg to 100 mg (one suppository) inserted into the vagina once or twice a day before ovulation. Your doctor may want patients to use medication to eleven weeks.
Side Effects
Depending on how much the progestin used, progestin can have different effects.For example, high doses of progesterone are needed for women who want to continue the pregnancy while progestins in low doses can prevent a pregnancy occurs.
Other effects can lead to weight gain, increased body temperature, increase the milk-producing glands for breast-feeding, and resting the uterus to maintain pregnancy.
Side effects are more common:
1. Increasing the amount of menstrual bleeding on monthly periods, lighter vaginal bleeding between menstrual periods, heavier vaginal bleeding between monthly periods, or stopping of menstrual periods.
2. Sperti blood sugar symptoms: dry mouth, frequent urination, loss of appetite, or unusual thirst.
Side effects are rarely encountered:
1. Mental depression
2. Skin rash
3. Milk flow increases with the unexpected
Sources: MayoClinic
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